In biological systems, enzymes create well-defined confined space to enforce catalytic activity with very high selectivities and precision. Even though all enzymatic activities are not well understood so far, it is mostly assumed that the confinement effect reduces the activation barrier by pre-organizing the reactants which facilitate their catalytic activities. Inspired by enzymatic functions we are interested in creating unique artificial molecular hosts for host-guest chemistry, sensing, drug delivery, and catalysis to explore their confined environment.
Rabban
Ph.D. Scholar