Mass spectrometry core | Department of Chemistry

Mass spectrometry core

  • LC-MS

The Mass Spectrometry Core facility provides state-of-the-art LC-MS service to identify structural analysis of small synthetic and biological molecules.

The Mass Spectrometry Core Facility is supported by Shiv Nadar University, School of Natural sciences as an advanced shared instrument facility for the benefit of SNU and the local research community.
Our mission is to provide state-of-the-art LC-MS service to students, fellows and faculty for identification and structural analysis of small synthetic and biological molecules and for qualitative and quantitative assays of drugs and metabolites in physiologic fluids. The facility is operated as an open-access core laboratory in which users are encouraged to run their own samples with the advice and assistance of Core personnel. Low cost service fees are charged for sample analysis from non-SNU users. Consultation, collaboration and data interpretation are available as professional courtesy at no charge.

Current Infrastructure:

  1. Agilent 6540 UHD Accurate-Mass Q-TOF LC/MS
  2. Agilent 1290 UPLC system
  3. An autosampler and diode array detector

Current Capabilities:

  1. Small Molecule HRMS
  2. Small molecule structure elucidation from HRMS/MS and fragmentation analysis
  3. Analysis of complex small molecule mixtures and identification of molecules using LC-MS/MS
  4. Method development for small molecule detection from quantitation
  5. Analysis of sequencing peptides and protein using LC-MS and LC-MS/MS
  6. Analysis and sequencing of oligonucleotides using LC-MS and LC-MS/MS


Lab Equipments